APPLICATIONS OF TECHNOLOGY: DNA synthesis ABSTRACT: Oligonucleotides are almost exclusively synthesized using the nucleoside phosphoramidite method, even though it is limited to the direct synthesis of ~200 mers and produces hazardous waste. Researchers at the Joint BioEnergy Institute (JBEI) have developed an oligonucleotide synthesis strategy that uses the … [Read more...] about DNA Synthesis Using Tethered dNTPs 2018-103
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DNA Construction by Single-molecule Assembly of Capped DNA Units 2013-188
APPLICATIONS OF TECHNOLOGY: Bioengineering ADVANTAGES: Potentially speed DNA synthesis while reducing costs ABSTRACT: Researchers at the Joint BioEnergy Institute (JBEI) have developed a technology for single-molecule construction of DNA. The invention provides for a method comprising: a) providing a reaction chamber comprising a solid support bound to a … [Read more...] about DNA Construction by Single-molecule Assembly of Capped DNA Units 2013-188
Unique Isoprenoid-like Compounds (Carbon Numbers Not in Multiples of Five) 2014-119
APPLICATIONS OF TECHNOLOGY: Biofuel production Semi-synthetic drug synthesis Flavor and fragrance production ADVANTAGES: Enables diverse functionalization of terpenoid structures Increases the diversity of chemicals available Reduces costs of chemical production ABSTRACT: A Joint BioEnergy Institute (JBEI) research team led by Jay Keasling has … [Read more...] about Unique Isoprenoid-like Compounds (Carbon Numbers Not in Multiples of Five) 2014-119
Converting Depolymerized Lignin into Value-added Products 2015-057
APPLICATIONS OF TECHNOLOGY: Biofuel/chemical production from lignocellulosic feedstocks ADVANTAGES: Reduces capital costs at a lignocellulosic biorefinery Efficient low-carbon emission ABSTRACT: Efficient conversion of lignocellulose requires the utilization of all its primary components (cellulose, hemicellulose, and lignin), yet no microbe in commercial … [Read more...] about Converting Depolymerized Lignin into Value-added Products 2015-057
JTherm for Enhanced Deconstruction of Lignocellulosic Biomass 2015-010
APPLICATIONS OF TECHNOLOGY: Biofuel production ADVANTAGES: Eliminates need for cellobiohydrolase Potential to replace other cellulase sources for biomass pretreatment and saccharification ABSTRACT: Active components of the JTherm enzymatic cocktail have been identified by JBEI, enabling heterologous production of critical enzymes to enable new, … [Read more...] about JTherm for Enhanced Deconstruction of Lignocellulosic Biomass 2015-010