APPLICATIONS OF TECHNOLOGY: Fig.1. Down regulation of Id-1 reduces metastatic spread. Prognostic marker for invasive and metastatic cancers Therapeutic target for the suppression of invasive and metastatic cancers ADVANTAGES: Provides a highly accurate marker for invasive and metastatic cancers Identifies Id-1, a key transcriptional regulator, as a target … [Read more...] about Prognostic for Invasive and Metastatic Cancers IB-1637
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Synthetic Peptide that Causes Bundling of F-Actin in Vitro and in Situ IB-1571
APPLICATION OF TECHNOLOGY: Pharmaceutical to block cell division of rapidly growing cancer cells Pharmaceutical to block rapid spread of certain highly pathogenic bacteria and viruses Pharmaceutical to prevent metastasis Basic research tool to study the role of the actin cytoskeleton in various in vivo and in vitro processes ADVANTAGES: Synthetic … [Read more...] about Synthetic Peptide that Causes Bundling of F-Actin in Vitro and in Situ IB-1571
Polymerized Nanoparticle Therapeutics IB-1056
Ernest Orlando Lawrence Berkeley National Laboratory APPLICATIONS OF TECHNOLOGY: Drug delivery Therapeutic potential for inflammatory … [Read more...] about Polymerized Nanoparticle Therapeutics IB-1056
Mouse Model for Common Genetic Risk Factor for Cardiovascular Disease IB-2789
APPLICATIONS OF TECHNOLOGY: Research of cardiovascular disease treatment and prevention methods ADVANTAGES: Provides new targets for coronary artery disease (CAD) and cancer drugs Enables new research avenues in Coronary artery disease and cancer Cdkn2a/b and other cyclin-dependent kinase inhibitors Disease mechanisms involving non-coding … [Read more...] about Mouse Model for Common Genetic Risk Factor for Cardiovascular Disease IB-2789
Transgenic Mice for Modeling Male Infertility IB-1202
Ernest Orlando Lawrence Berkeley National Laboratory APPLICATIONS OF TECHNOLOGY: Research on male infertility Development of male contraceptives ADVANTAGES: Provides homogeneous experimental groups Heterozygotes remain fertile, … [Read more...] about Transgenic Mice for Modeling Male Infertility IB-1202