APPLICATIONS OF TECHNOLOGY:
- Bioengineering
ADVANTAGES:
- Potentially speed DNA synthesis while reducing costs
ABSTRACT:
Researchers at the Joint BioEnergy Institute (JBEI) have developed a technology for single-molecule construction of DNA. The invention provides for a method comprising: a) providing a reaction chamber comprising a solid support bound to a single starter double-stranded (ds) DNA molecule comprising a free end, b) introducing one or more extension molecules and one or more enzymes capable of joining a payload region of an extension molecule to the free end of starter dsDNA molecule to the reaction chamber wherein the extension molecule comprises a cleavable linker.
For details regarding this invention, see Published U. S. Patent Application #15,/311,846 (Publication No. US2017/0218416).
STATUS: Published U. S. Patent Application #15,/311,846 (Publication No. US2017/0218416). Available for licensing or collaborative research.