APPLICATIONS OF TECHNOLOGY: Drug binding assays ADVANTAGES: Enables rapid drug binding analyses Reduces cost and time to conduct complex, data-intensive drug experiments Applicable across a wide range of experimental conditions ABSTRACT: Researchers led by Berkeley Lab’s Alex Pines have developed a faster and more sensitive technology to characterize … [Read more...] about Xenon-based Drug Protein Binding Assay 2016-165
Research Tools
Low Field Xenon NMR 2016-166
APPLICATIONS OF TECHNOLOGY: Drug binding assays Protein assays Other chemical and biological analysis ADVANTAGES: Enables xenon NMR in miniaturized assays and portable devices ABSTRACT: Berkeley Lab’s Alex Pines and a team of researchers have developed a technology to use hyperpolarized xenon at low magnetic fields – on the order of the Earth’s magnetic … [Read more...] about Low Field Xenon NMR 2016-166
ARGO: Peptide Barcoding for Genomic Discovery 2015-123
APPLICATIONS OF TECHNOLOGY: Biomanufacturing of enzymes Enzyme research ADVANTAGES: Rapid discovery of the function of genes Capable of multiplexing Ultra-high-throughput ABSTRACT: Researchers at Berkeley Lab led by Trent Northen have developed the ARGO (Assignment of the Reactions of Gene products in Organisms) platform, an efficient and scalable … [Read more...] about ARGO: Peptide Barcoding for Genomic Discovery 2015-123
Lanthanide-Chelator Barcode for Combinatorial Screening Applications 2016-121
APPLICATIONS OF TECHNOLOGY: Combinatorial screening in Drug discovery and optimization Biomanufacturing Diagnostics ADVANTAGES: Enables faster testing of more diverse conditions / combinations Readily detects lanthanide/chelator complexes Maintains strong lanthanide binding and single-charge ionization Simplified … [Read more...] about Lanthanide-Chelator Barcode for Combinatorial Screening Applications 2016-121
Identifying Organism Interactions with High Throughput Enrichment Culturing 2016-132
APPLICATIONS OF TECHNOLOGY: Microbial community engineering to Improve agricultural yields Design probiotic applications in humans or livestock Engineer increased industrial fermentor yields ADVANTAGES: Simultaneously evaluates all possible interactions from a mixed consortia High throughput Accurate ABSTRACT: Adam Arkin and Nicholas Justice of … [Read more...] about Identifying Organism Interactions with High Throughput Enrichment Culturing 2016-132