APPLICATIONS: Synthetic biology Biotechnology research ADVANTAGES: Design tool for both guide RNA and for CRISPR sequences Models secondary structures ABSTRACT: Researcher Sarah Richardson of the Joint BioEnergy Institute (JBEI) has developed Toaster, a software program that designs Cas9 targeting reagents for non-human model organisms. Given a genome … [Read more...] about Toaster Software: Optimizing CRISPR Technologies for Genome Editing 2016-056
Research Tools
Boron Nitride Nanopores for DNA Sequencing, Water Desalination and Gas / Liquid Separation 2015-045
APPLICATIONS OF TECHNOLOGY: DNA sequencing for large scale clinical applications Molecular analysis for chemical manufacturing Water desalination Gas / liquid separation for manufacturing of batteries, air filtration devices, and alcohol ADVANTAGES: More scalable than biological nanopores Repeatable shape and size (as small as a single … [Read more...] about Boron Nitride Nanopores for DNA Sequencing, Water Desalination and Gas / Liquid Separation 2015-045
Basal Media for Culturing Epithelial Cells 2015-009
APPLICATIONS: Growing primary human epithelial cells for Pharmaceutical development Toxicology Biotechnology research ADVANTAGES: Regular and consistent formulation Superior growth for 1/12 of the price Up to 60 population doublings Can sustain long term cultures ABSTRACT: Researchers at Berkeley Lab have developed a low cost technology for growing … [Read more...] about Basal Media for Culturing Epithelial Cells 2015-009
Precise, High Throughput Droplet Manipulation 2013-128
APPLICATIONS: Research – pharmaceutical, enzyme, genetics ADVANTAGES: Can screen an extremely large number of biological samples Capable of evaluating multiple experimental conditions at one time Generates droplets quickly and efficiently based on various characteristics Utilizes new and effective droplet mixing and sorting … [Read more...] about Precise, High Throughput Droplet Manipulation 2013-128
Consistent, Reliable Preparation of Cryo-EM Specimens 2015-108
APPLICATIONS: Preparation of biological samples for electron microscopy ADVANTAGES: Enables consistent and reliable production of samples Thickness of cryo-EM specimens is uniform across the grid Facilitates the production of extremely thin samples Potentially damaging sample evaporation not required ABSTRACT: Researchers at Berkeley Lab have … [Read more...] about Consistent, Reliable Preparation of Cryo-EM Specimens 2015-108