Innovation and Partnerships Office

Licensed Berkeley Lab Techs Poised to Advance Heart Health, Drug Discovery

May 25, 2016

Berkeley Lab’s Innovation and Partnerships Office executed licensing agreements this spring to move two biotechnologies from the lab to the marketplace. The Engevity Cuff, developed by Berkeley Lab researcher Jonathan Maltz, improves cardiovascular disease diagnosis by measuring endothelial health and plaque buildup. Startup Lexington Biosciences will refine and commercialize the cuff design. OpenMSI leverages Big Data resources to analyze, visualize, manage  and share MSI data in real time, anywhere in the world, promising to advance disease diagnostics and therapeutics, among other biotech applications. Imabiotech licensed Open MSI intellectual property to support its own imaging platform.

The Enegevity Cuff measures blood vessel health.

The Enegevity Cuff measures blood vessel health.

OpenMSI enables real time analysis and data sharing for enormous mass spectrometry image files

OpenMSI enables real time analysis and data sharing for enormous mass spectrometry image files

DOE / Berkeley Lab to Participate in 2016 Maker Faire

May 16, 2016


Join Berkeley Lab staff at DOE’s Make|Energy pavilion at Bay Area Maker Faire, May 20-22, in San Mateo. The Lab plus eight other DOE labs, DOE’s Office of Technology Transitions, ARPA-E and EERE will present hands-on and educational displays related to Energy Generation, Secure Energy Distribution, Smart Buildings & Cities, and Manufacturing to demonstrate how DOE science improves the world. See DOE’s Maker Faire page for more information about technologies on display.

An Ask a Scientist booth will be staffed by DOE researchers — including genomics, computing sciences, and energy storage experts from Berkeley Lab — to answer attendees’ science and energy questions.  Berkeley Lab’s Chief Technology Transfer Officer, Elsie Quaite-Randall, and other DOE leaders will participate in a panel discussion on DOE’s programs to transition technologies from lab to market. Researcher Ronald Zuckerman joins other DOE scientists on a Think-Make-Innovate panel, and Reshma Singh leads a panel on Jump, DOE’s new tech crowdsourcing program.

DOE Make|Energy pavilion highlights include –

–a “Fight the Hackers” challenge modeling how cyber security protects the energy grid

–algae-fueled boat races

–a full size, 3D-printed Jeep

–mini-microscopes that attach to cell phones

–windmill-powered cell phone charging

–an array of smart technologies enabling energy efficient buildings and communities

plus live demonstrations of DOE technologies from ESNet to water-cooled shoes and 3D visualization tools.


Berkeley Lab Startups in the News

May 11, 2016

increaseA May 4 article in The New Yorker on the quest to achieve true color representations in electronic displays highlighted quantum dot technology and innovations by Berkeley Lab startup Nanosys.

Second Genome, a startup based on Berkeley Lab technology, earned $42.6M in Series B round funding from the venture capital arms of Pfizer and Roche along with other investors. The company is testing a drug to treat inflammation and pain associated with ulcerative colitis, developing other therapeutics based on its microbiome research, and sequencing microbial genomes for pharmaceutical and biotech companies with its proprietary platform. Second Genome employs 26 people.

Dow AgroSciences will partner with Berkeley Lab startup TeselaGen Biotechnology to build a platform to speed discovery in new crop protection and seed products. TeselaGen offers a platform to generate cost-optimized DNA construction protocols anticipated to cut the time to identify new lead molecules for Dow’s sustainable agriculture solutions from years to months.


Startup Licenses Berkeley Lab Cardiovascular Health Device

March 17, 2016


Jonathan Maltz, Ph.D., Molecular Biophysics and Integrated Bioimaging

New startup Lexington Biosciences exclusively licensed the Berkeley Lab Enegevity Cuff, a technology to dramatically advance the testing and monitoring of cardiovascular health. The device, developed by Berkeley Lab’s Jonathan S. Maltz, Ph.D., measures arterial lining health to assess plaque buildup and atherosclerosis quickly and easily, outside a clinical setting. A Berkeley Lab Innovation Grant enabled Maltz to advance the invention by funding construction of a prototype cuff and clinical testing to prove the device’s superior sensitivity compared to ultrasound results. Lexington Biosciences will further refine the Enegevity Cuff design, complete clinical testing, and initiate the Food and Drug Administration (FDA) approval process as quickly as practical. 

Cardiovascular disease and stroke are the number one causes of death worldwide, according to the World Health Organization. Early assessment and monitoring of blood vessel health to inform preventative care and lifestyle modification is an important step towards reducing heart disease risk. Routine blood pressure and cholesterol testing do not evaluate arterial lining health. Yet plaque deposits breaking away from inner artery walls, ultimately blocking blood flow downstream, kill more people than all cancers combined. The automated Enegevity Cuff is compact and easy to use, expanding the availability of this important cardiovascular testing to physician’s offices, even patient’s homes.


IPO – Your Gateway to Berkeley Lab Innovation

February 25, 2016

Partnership_Brochure_IPOThe Innovation and Partnerships Office has created an updated guide highlighting Berkeley Lab’s areas of expertise, the wide range of partnership options available, and selected startup, licensing, partnership and industry consortia success stories.


IPO Licensing Associate Honored

February 19, 2016

Matthew Love, IPO Licensing Associate

Matthew Love, IPO Licensing Associate

Matthew Love, Licensing Associate with Berkeley Lab’s Innovation and Partnerships Office, received a Federal Lab Consortium award for a technology transfer project to advance Columnar Hierarchical Auto-associative Memory Processing in Ontological Networks (CHAMPION), a hierarchical structure of modified Case-Based Reasoning components at former employer, PNNL. Now with Berkeley Lab’s IPO, Matthew negotiates licenses for technologies in the energy and physical sciences areas with potential startups and industry partners.




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