APPLICATIONS OF TECHNOLOGY: • Point-of-care clinical diagnostics • Remote sensing of hazardous materials • Toxic gas leak detection • Physical incorporation into cell phones or small devices for remote detection, e.g., drones ADVANTAGES: • High specificity in analyte identification • Small in size for field portability • Low power requirement and cost • … [Read more...] about PUMA: Ultrasensitive Detection of Biological and Chemical Agents 2017-054
Diagnostics
Spectroscopic Imaging and Analysis of Live Cells 2015-077
ABSTRACT: Researchers at Berkeley Lab led by Hoi-Ying Holman have developed technologies for measurement, visualization, and analysis of chemical dynamics in living cells or tissues for diagnostic pathology. Devices can be open- or closed-channel microfluidic membrane devices for long-term IR spectroscopy of live adherent cells and ultimately for rapidly identifying … [Read more...] about Spectroscopic Imaging and Analysis of Live Cells 2015-077
A Novel 12-Gene Prognostic Signature for Breast Cancer 2016-181
APPLICATIONS OF TECHNOLOGY: Targeted cancer therapies Prediction of relapse-free survival ADVANTAGES: Determines most effective treatment options for patient quality of life Standardizes breast cancer prognoses ABSTRACT: A Berkeley Lab research team led by Antoine Snijders has identified a 12-gene signature that can be used to predict relapse-free … [Read more...] about A Novel 12-Gene Prognostic Signature for Breast Cancer 2016-181
OpenPET Readout Electronics for Radionuclide Imaging 2015-152
APPLICATIONS: Medical imaging Homeland security Other imaging applications ADVANTAGES: High performance - timing resolution, spatial resolution, energy resolution, throughput Supports any kinds of detector and camera configuration Supports virtually any size imager Easily modified via software ABSTRACT: OpenPET is an open source, modular, … [Read more...] about OpenPET Readout Electronics for Radionuclide Imaging 2015-152
Lanthanide-Chelator Barcode for Combinatorial Screening Applications 2016-121
APPLICATIONS OF TECHNOLOGY: Combinatorial screening in Drug discovery and optimization Biomanufacturing Diagnostics ADVANTAGES: Enables faster testing of more diverse conditions / combinations Readily detects lanthanide/chelator complexes Maintains strong lanthanide binding and single-charge ionization Simplified … [Read more...] about Lanthanide-Chelator Barcode for Combinatorial Screening Applications 2016-121