Applications of Technology: Improved radiotherapy dose delivery and control Materials analysis and characterization High-precision nuclear and particle physics experiments Benefits: More precise tumor targeting, reduced unnecessary radiation exposure Minimal modifications to cyclotron systems Utilization of off-the-shelf high-voltage … [Read more...] about Cost-Effective Single-Bunch Extraction Technique for Cyclotrons 2024-051
Human Health/Precision Medicine
Novel Transcriptional Activator Domains from Plants and Yeast To Enhance Eukaryotic Gene Expression 2023-135
Applications: Increased protein expression yields in plants and fungi Development of drought-resistant crops Streamlined method to develop new genetic tools and genome-scale activation assays Advantages: Equal or stronger activity than the current state of the art activation domains Quick integration of regulatory domains into known and novel expression … [Read more...] about Novel Transcriptional Activator Domains from Plants and Yeast To Enhance Eukaryotic Gene Expression 2023-135
High-precision Pipette Tips Compatible with Existing Liquid Handling Robots 2023-014
APPLICATIONS OF TECHNOLOGY: Mass spectrometry High-density microarray applications Food and pharmaceutical laboratory research BENEFITS: Rapid and accurate high-throughput testing More repeatable than manual pipetting Ensures more efficient and complete sample transfer Reduced risk of sample loss or contamination Ability to interface with existing … [Read more...] about High-precision Pipette Tips Compatible with Existing Liquid Handling Robots 2023-014
Genetically Modified Host Cells for Improved Polyketide Production 2022-152
APPLICATIONS OF TECHNOLOGY: High-value products using methylmalonyl-CoA as substrate: Erythromycin (antibiotic) and spinosyn (insecticide) Germicidin, which has significant inhibitory activity on hexokinase which is expressed at a high level in cancer cells Novel recyclable materials Flavors and fragrances Commodity or specialty chemicals ADVANTAGES: … [Read more...] about Genetically Modified Host Cells for Improved Polyketide Production 2022-152
Chelating Ligands for Enhanced Radiolabeling and Therapeutic Potential 2023-119
APPLICATIONS OF TECHNOLOGY: Development of radiopharmaceuticals for cancer diagnosis and treatment Development of antibodies labeled with radionuclides BENEFITS: Simplified synthesis compared to other structures Faster radiolabeling at room temperature Formation of highly stable radiometal complexes Higher synthetic yields BACKGROUND: Thorium-227 … [Read more...] about Chelating Ligands for Enhanced Radiolabeling and Therapeutic Potential 2023-119