APPLICATIONS OF TECHNOLOGY: Phage engineering Cataloging and Control of phages Diagnosis and Antibiotic Discovery ADVANTAGES: No interference of the phage infection cycle No compromise of the host bacteria life cycle Enables easy amplification of the DNA “barcode” for identification, tracking and control of individual phages Standardizes the workflow … [Read more...] about Novel Methods for the Barcoding of Bacteriophages 2019-113
Human Health/Precision Medicine
Synthesis of Gold Nanoparticles Functionalized with 3,4,3-LI(1,2-HOPO) Chelator for Metal Sensing 2020-033
APPLICATIONS OF TECHNOLOGY: Detection of toxic lanthanide and actinides in environmental and waste samples Detection and quantification of f-block elements used as contrast agents in biomedicine ADVANTAGES: High affinity and specificity with f-block elements Single step method The only synthetic protocol to obtain gold nanoparticles functionalized with … [Read more...] about Synthesis of Gold Nanoparticles Functionalized with 3,4,3-LI(1,2-HOPO) Chelator for Metal Sensing 2020-033
Gut Microbiome Engineering for the Heterologous Production of Antiviral Compounds 2019-085
APPLICATIONS OF TECHNOLOGY: Medical: Pharmaceuticals ADVANTAGES: Present strain is among the most robust constituents of the gut microbiome Obviates the need for exogenous iron-sulfur cluster producing genetic elements ABSTRACT: In 2018, Gizzi et al. demonstrated that the human gene Viperin can produce antiviral small molecules (ddhCTP) that act as a chain … [Read more...] about Gut Microbiome Engineering for the Heterologous Production of Antiviral Compounds 2019-085
Polysaccharide Gel 2017-041
APPLICATIONS OF TECHNOLOGY: Food products Cosmetics Water and wastewater treatment Pharmaceuticals BENEFITS: Significantly lowers the costs of product recovery from cyanobacterial production strains Self-aggregating properties of the material streamline the processes of flocculation and clarification Enables novel encapsulation and drug formulation … [Read more...] about Polysaccharide Gel 2017-041
Metabolite, Annotation and Gene Integration System (MAGI) and Software 2017-063, 2017-105
APPLICATIONS: Genomics research BACKGROUND: Metabolomics has been used for obtaining direct measures of metabolic activities from diverse biological systems. However, metabolomics can be limited by ambiguous metabolite identifications. Furthermore, interpretation can be limited by incomplete and inaccurate genome-based predictions of enzyme activities (e.g., gene … [Read more...] about Metabolite, Annotation and Gene Integration System (MAGI) and Software 2017-063, 2017-105