APPLICATIONS: Genomics research BACKGROUND: Metabolomics has been used for obtaining direct measures of metabolic activities from diverse biological systems. However, metabolomics can be limited by ambiguous metabolite identifications. Furthermore, interpretation can be limited by incomplete and inaccurate genome-based predictions of enzyme activities (e.g., gene … [Read more...] about Metabolite, Annotation and Gene Integration System (MAGI) and Software 2017-063, 2017-105
Human Health/Precision Medicine
Peptoid-Based Chelating Molecules 2017-181
APPLICATIONS OF TECHNOLOGY: Radiolabeling Metal separation Water treatment ADVANTAGES: Robust chelators High selectivity ABSTRACT: Researchers led by Rebecca Abergel have developed a new class of chelators – molecules that can bind metals – that incorporate peptoids into the chelator backbone, offering more control over the chelator’s structure and … [Read more...] about Peptoid-Based Chelating Molecules 2017-181
High-Throughput Methods to Characterize Phage Receptors and Rational Formulation of Phage Cocktails 2019-048
APPLICATIONS OF TECHNOLOGY: Pharmaceutical / antibiotic discovery Phage therapy ADVANTAGES: Compared to current technologies Less expensive Less laborious Scalable Quantitative ABSTRACT: Researchers at the Berkeley Lab have developed two genetic technologies that enable fast and effective genome-wide screens for gene function. The LBNL … [Read more...] about High-Throughput Methods to Characterize Phage Receptors and Rational Formulation of Phage Cocktails 2019-048
Production of Impurity-free Actinium-225 for Cancer Treatment 2019-040
APPLICATIONS OF TECHNOLOGY: Radiopharmaceuticals ADVANTAGES: Efficient, inexpensive, and scalable process No co-production of radioactive impurities to hinder use in patients Long half-life 4 α-decays capable of producing the sort of double-strand DNA damage needed to deter tumor growth Produces no long-lived radioactive products in its … [Read more...] about Production of Impurity-free Actinium-225 for Cancer Treatment 2019-040
Improving High Value Carotenoid Astaxanthin Production 2017-033
APPLICATIONS OF TECHNOLOGY: Human health and nutrition Biofuel feedstocks Food production ADVANTAGES: More economically viable means to produce microalgae Identifies specific genes required for astaxanthin antioxidant synthesis ABSTRACT: Researchers led by Melissa Roth of Howard Hughes Medical Institute and Krishna Niyogi of the Berkeley Lab have … [Read more...] about Improving High Value Carotenoid Astaxanthin Production 2017-033