ABSTRACT: Global photosynthetic productivity is limited by the enzymatic assimilation of CO2 into organic carbon compounds. Ribulose-1,5- bisphosphate carboxylase/oxygenase (RuBisCO), the carboxylating enzyme of the Calvin-Benson (CB) cycle, poorly discriminates between CO2 and O2, leading to photorespiration and the loss of fixed carbon and nitrogen. With the advent of … [Read more...] about Introduction of a Synthetic CO2-fixing Photorespiratory Bypass into a Cyanobacterium 2013-020
Biotechnology
Production of Bacterial Microcompartments for Synthetic Biology Applications IB- 2013-014
APPLICATIONS OF TECHNOLOGY: Biotechnology Carbon capture and sequestration Biofuels production Drug delivery Specialty chemical manufacturing Vaccine development ADVANTAGES: Small, uniform geometries Long lasting (> 2 months) Semipermeable membrane walls Allows engineered pore selectivity Does not rely on natural operon sequences Well … [Read more...] about Production of Bacterial Microcompartments for Synthetic Biology Applications IB- 2013-014
Enhanced Production of Biofuel Precursors in Microalgae 2013-075
APPLICATIONS OF TECHNOLOGY: Oil / biodiesel production Algal strain improvement and targeted engineering Agriculture industries Biotech research, e.g. identifying master regulators for stress-elicited responses ADVANTAGES: Simultaneously maximizes both algal growth and lipid accumulation Covers large numbers of genes in multiple pathways ABSTRACT: A … [Read more...] about Enhanced Production of Biofuel Precursors in Microalgae 2013-075
Production of Fatty-Acid-Derived Biofuels and Chemicals in Saccharomyces cerevisiae 2013-113
APPLICATIONS OF TECHNOLOGY: Green source of Biofuels Polymers Lubricants Cosmetics, flavors, fragrances Pharmaceuticals ADVANTAGES: S. cerevisiae more genetically tractable than microalgae or oleaginous yeast Mutant strains easy to generate, isolate, analyze Proven track record of S. cerevisiae in industrial applications Readily … [Read more...] about Production of Fatty-Acid-Derived Biofuels and Chemicals in Saccharomyces cerevisiae 2013-113
Using Polyketide Synthases to Produce Advanced Biofuels EJIB-2540
APPLICATIONS OF TECHNOLOGY: Biosynthesis of carboxylic acids and lactones for biofuel production ADVANTAGES: Provides biofuel alternatives to ethanol The polyketide synthases can be modified to tailor-make a wide variety of lactones and carboxylic acids Controlled placement of ester linkages may result in enhanced combustion properties Esters and lactones are … [Read more...] about Using Polyketide Synthases to Produce Advanced Biofuels EJIB-2540