APPLICATIONS OF TECHNOLOGY: Early identification of cardiovascular disease Endothelial function assessment ADVANTAGES: Easy to operate; no need for trained technician Facilitates regular patient testing and feedback More sensitive than conventional flow-mediated vasodilation (FMD) measurement Inexpensive to manufacture Fully automated test … [Read more...] about Assessing Endothelial Function with a Standard Blood Pressure Cuff IB-2772
Diagnostics
Acid-Degradeable and Bioerodible Materials JIB-2595
APPLICATIONS OF TECHNOLOGY: Drug delivery, including controlled-release formulations Vaccine and immunotherapy Gene therapy Chemotherapy Sutures, scaffolds, and implantable bulk materials Diagnosis and imaging ADVANTAGES: Site-specific delivery, accurate therapeutic targeting Payload release or degradation rate can be tuned easily—from minutes to hours to … [Read more...] about Acid-Degradeable and Bioerodible Materials JIB-2595
ANXA9: A Therapeutic Target and Predictive Marker for Early Detection of Aggressive Breast Cancer JIB-2371
APPLICATIONS OF TECHNOLOGY: Breast cancer diagnosis Treatment of aggressive breast cancer and cancer resistant to chemotherapy ADVANTAGES: Prevents aggressive breast cancers from metastasizing Offers early detection of aggressive breast cancers May increase survival rates of breast cancer patients May improve response to chemotherapy … [Read more...] about ANXA9: A Therapeutic Target and Predictive Marker for Early Detection of Aggressive Breast Cancer JIB-2371
Protease-based Cancer Screening Using Nanoliter Samples IB-2240
APPLICATIONS OF TECHNOLOGY: Early stage screening of cancers via detection of proteases and proteolytic activity in fluid or biopsy samples Prostate cancer detection, and possibly the detection of other protease-related cancers such as breast, colon, kidney, skin, stomach, ovary, and lung cancer ADVANTAGES: Nanoliter sample volumes Reduces false positives for … [Read more...] about Protease-based Cancer Screening Using Nanoliter Samples IB-2240
At-Home Test Kit and Lab Analysis for DNA Damage Assessment 2014-044
An at-home blood collection kit that immediately fixes blood cells’ biological activity enabling non-toxic sample shipment or storage without changes in specific DNA markers. Samples are treated and assessed in an automated, high-throughput, reproducible process yielding results that take each patient’s age, health status and exposure history into account. APPLICATIONS DNA … [Read more...] about At-Home Test Kit and Lab Analysis for DNA Damage Assessment 2014-044