APPLICATIONS OF TECHNOLOGY: Cancer diagnostics and therapy ADVANTAGES: Fast, accurate, and affordable Improves tumor staging and patient stratification for most cancers ABSTRACT: Berkeley Lab researcher Heinz-Ulrich Weier has developed Genetic Barcodes, a fluorescent in situ hybridization (FISH)-based assay offering affordable diagnostics for the early … [Read more...] about Genetic Barcodes for Cancer Prediction and Prognosis IB-2897
Diagnostics
Assessing Endothelial Function with a Standard Blood Pressure Cuff IB-2772
APPLICATIONS OF TECHNOLOGY: Early identification of cardiovascular disease Endothelial function assessment ADVANTAGES: Easy to operate; no need for trained technician Facilitates regular patient testing and feedback More sensitive than conventional flow-mediated vasodilation (FMD) measurement Inexpensive to manufacture Fully automated test … [Read more...] about Assessing Endothelial Function with a Standard Blood Pressure Cuff IB-2772
Acid-Degradeable and Bioerodible Materials JIB-2595
APPLICATIONS OF TECHNOLOGY: Drug delivery, including controlled-release formulations Vaccine and immunotherapy Gene therapy Chemotherapy Sutures, scaffolds, and implantable bulk materials Diagnosis and imaging ADVANTAGES: Site-specific delivery, accurate therapeutic targeting Payload release or degradation rate can be tuned easily—from minutes to hours to … [Read more...] about Acid-Degradeable and Bioerodible Materials JIB-2595
ANXA9: A Therapeutic Target and Predictive Marker for Early Detection of Aggressive Breast Cancer JIB-2371
APPLICATIONS OF TECHNOLOGY: Breast cancer diagnosis Treatment of aggressive breast cancer and cancer resistant to chemotherapy ADVANTAGES: Prevents aggressive breast cancers from metastasizing Offers early detection of aggressive breast cancers May increase survival rates of breast cancer patients May improve response to chemotherapy … [Read more...] about ANXA9: A Therapeutic Target and Predictive Marker for Early Detection of Aggressive Breast Cancer JIB-2371
Protease-based Cancer Screening Using Nanoliter Samples IB-2240
APPLICATIONS OF TECHNOLOGY: Early stage screening of cancers via detection of proteases and proteolytic activity in fluid or biopsy samples Prostate cancer detection, and possibly the detection of other protease-related cancers such as breast, colon, kidney, skin, stomach, ovary, and lung cancer ADVANTAGES: Nanoliter sample volumes Reduces false positives for … [Read more...] about Protease-based Cancer Screening Using Nanoliter Samples IB-2240