A subject's arm is shown positioned on the platform of the Berkeley Lab instrument. Artificial pulses are applied by the actuator and detected by an ultrasound probe. APPLICATIONS OF TECHNOLOGY: Detects cardiovascular disease (CVD) at the preclinical stage by measuring vasorelaxation Monitors the effects of statins and other drugs, vitamins, … [Read more...] about Noninvasive Detection of Preclinical Cardiovascular Disease IB-1796
Diagnostics
Quantum Dot Based Cell Motility, Invasion, and Metastasis Assays IB-1755
APPLICATIONS OF TECHNOLOGY: Rapid method for assaying metastatic potential in biopsies Cancer drug development Research on cell motility ADVANTAGES: More photochemically robust than organic dyes Less labor intensive than the Boyden Chamber invasion assay Can be used with live cells no fixation/processing required Allows for real time variation of external … [Read more...] about Quantum Dot Based Cell Motility, Invasion, and Metastasis Assays IB-1755
Prognostic for Invasive and Metastatic Cancers IB-1637
APPLICATIONS OF TECHNOLOGY: Fig.1. Down regulation of Id-1 reduces metastatic spread. Prognostic marker for invasive and metastatic cancers Therapeutic target for the suppression of invasive and metastatic cancers ADVANTAGES: Provides a highly accurate marker for invasive and metastatic cancers Identifies Id-1, a key transcriptional regulator, as a target … [Read more...] about Prognostic for Invasive and Metastatic Cancers IB-1637
Optical Atomic Magnetometer for Portable, Inexpensive MRI and Magnetic Microparticle Detection IB-2232
APPLICATIONS OF TECHNOLOGY: Low-cost MRI for noninvasive diagnostics Remote medical diagnostic detection by NMR and MRI Monitoring chemical reactions and biological processes using magnetic particles Detecting magnetic impurities for quality control on production lines Enabling studies of drug delivery for pharmaceutical development ADVANTAGES: High … [Read more...] about Optical Atomic Magnetometer for Portable, Inexpensive MRI and Magnetic Microparticle Detection IB-2232
Heart and Torso Phantom Model of Cardiac and Respiratory Motion for Nuclear Imaging IB-2358
APPLICATIONS OF TECHNOLOGY: Models the human torso, heart, and lungs for improving SPECT and PET imaging Develops and validates algorithms to correct for cardiac and respiratory motion in nuclear imaging Intermodality image registration Simultaneous modality imaging … [Read more...] about Heart and Torso Phantom Model of Cardiac and Respiratory Motion for Nuclear Imaging IB-2358