APPLICATIONS OF TECHNOLOGY: Ablation of target tissue Oncology imaging and treatment BENEFITS: Targeted delivery of nuclides for better imaging Precise and effective treatment for certain cancers that preserves surrounding cells and tissues BACKGROUND: Targeted alpha therapy is highly promising as a cancer treatment. It has the potential to deliver a … [Read more...] about Harnessing Siderocalin Compositions for Cancer Theranostics via Targeting and Chelation 2016-170
Human Health/Precision Medicine
Separation of Tetravalent Metal Ions using Protein-ligand-based Systems 2016-178
APPLICATIONS OF TECHNOLOGY: Pharmaceutical isotope production Water purification Nuclear waste treatment and portable analysis Production of radiation sources ADVANTAGES: Improved performance and reliability Versatile process Separates different metal ions under soft conditions Scalable and operable at room temperature BACKGROUND: Current … [Read more...] about Separation of Tetravalent Metal Ions using Protein-ligand-based Systems 2016-178
Rapid Detection of Gadolinium-Based Contrast Agents in Urine with a Chelated Europium Luminescent Probe 2020-072
APPLICATIONS OF TECHNOLOGY: Diagnostics and analytical chemistry Detection of gadolinium-based contrast agents in urine BENEFITS: Uses luminescence spectroscopy, a lower cost and more efficient method that does not require sample digestion and preparation compared to the industry standard that uses mass spectrometry Capable … [Read more...] about Rapid Detection of Gadolinium-Based Contrast Agents in Urine with a Chelated Europium Luminescent Probe 2020-072
Detecting Neurodegenerative Disease Using Skin Cells and Infrared Light 2021-126
APPLICATIONS OF TECHNOLOGY: Diagnostic tool for early detection of Alzheimer’s disease in living patients Disease class predictions in the absence of overt pathology Diagnostic for early detection of other neurodegenerative or neurological diseases Potential diagnostic tool for a broad range of illnesses, including COVID-19 and breast … [Read more...] about Detecting Neurodegenerative Disease Using Skin Cells and Infrared Light 2021-126
Discovery of Robust Cellular Morphometric Subtypes in Lower Grade Glioma through Machine Learning 2021-064
APPLICATIONS OF TECHNOLOGY: Identifying clinically significant subtypes for different tumors BENEFITS: Provides new knowledge that improves diagnosis and optimization of treatment Cost-effective compared with hematoxylin and eosin (H&E) stained histology sections Promises significant clinical value combined with well-known factors (i.e., clinical factors … [Read more...] about Discovery of Robust Cellular Morphometric Subtypes in Lower Grade Glioma through Machine Learning 2021-064