APPLICATIONS OF TECHNOLOGY: Combinatorial screening in Drug discovery and optimization Biomanufacturing Diagnostics ADVANTAGES: Enables faster testing of more diverse conditions / combinations Readily detects lanthanide/chelator complexes Maintains strong lanthanide binding and single-charge ionization Simplified … [Read more...] about Lanthanide-Chelator Barcode for Combinatorial Screening Applications 2016-121
Diagnostics and Therapeutics
Dub-seq: Double Barcoded Shotgun Expression Library Sequencing 2015-160
APPLICATIONS OF TECHNOLOGY: Drug discovery and screening Functional genomics Synthetic biology Enzyme discovery ADVANTAGES: High throughput Scalable Less labor intensive and expensive than current approaches Enables gene function annotation ABSTRACT: Though current functional genomics technologies coupled with next generation sequencing have … [Read more...] about Dub-seq: Double Barcoded Shotgun Expression Library Sequencing 2015-160
A Universal Approach to Integrate and Express Pathways in a Broad Range of Bacteria 2016-024
APPLICATIONS OF TECHNOLOGY: Microbiome engineering for medicine, agriculture, biomanufacturing and renewable energy Pharmaceutical synthesis Commodity chemical and biofuel production Livestock research and development ADVANTAGES: Enables high-throughput, stable, accurate, efficient gene integration and expression of very large DNA constructs (e.g., … [Read more...] about A Universal Approach to Integrate and Express Pathways in a Broad Range of Bacteria 2016-024
Strong, Long-Range, Aligned Lamellar Structures for Biomedical (Synthetic Bone) and Energy Applications 2015-018
APPLICATIONS: Synthetic bone scaffolding Water purification filters Fuel cell electrodes Tissue engineering ADVANTAGES: Strong, tough, and lightweight Anisotropic properties that mimic natural materials Appropriate for many composite materials ABSTRACT: Researchers working in Berkeley Lab’s Materials Sciences Division have developed … [Read more...] about Strong, Long-Range, Aligned Lamellar Structures for Biomedical (Synthetic Bone) and Energy Applications 2015-018
Selective Modification of Proteins 2015-038
APPLICATIONS: Pharmaceutical therapeutics Biochemical sensors Building blocks for bio-based materials ADVANTAGES: Provides well defined method of modification Site specific Allows for control of the degree of modification ABSTRACT: Researchers at Lawrence Berkeley National Lab and the University of California, Berkeley have developed a technology … [Read more...] about Selective Modification of Proteins 2015-038