APPLICATIONS OF TECHNOLOGY: Bone growth promotion Bone growth and mineralization inhibition Potential osteoporosis treatment Cell-based treatment of bone defects Structural materials ADVANTAGES: Collagen-mimicking oligopeptides induce mineralization Sequence-dependent bone mineral binding capabilities are controllable Peptides can be incorporated into a … [Read more...] about Peptides for the Controllable Promotion or Inhibition of Bone Growth IB-2080
Diagnostics and Therapeutics
FlexBone: Osteo-mimetic Composites IB-2104
Berkeley Lab's flexible hydrogel-HA composite, FlexBone, has a mineral-to-organic matrix ratio approximating that of human bone. The material can be bent, compressed, and further processed to create products with a wide range of mechanical properties. APPLICATIONS OF TECHNOLOGY: Bone implants Dental implants Bio-cements Flexible composites with magnetic … [Read more...] about FlexBone: Osteo-mimetic Composites IB-2104
Injectable Hydrogel-Based Biodegradable Bone Replacement Materials IB-2398
APPLICATIONS OF TECHNOLOGY: Bone implants Dental implants Injectable bone cements Drug delivery Scaffolds for bone tissue engineering ADVANTAGES: Promotes natural bone growth as it biodegrades Improves mechanical performance and tissue-implant interactions of orthopedic materials Simplifies application with injectable slurry that solidifies at target … [Read more...] about Injectable Hydrogel-Based Biodegradable Bone Replacement Materials IB-2398
Human Blood Molecular Biodosimeter Panel for Distinguishing Radiation Exposure from Inflammation Stress IB-3304
APPLICATIONS OF TECHNOLOGY: Radiation oncology Medical triage Rapid response in cases of population exposure to ionizing radiation ADVANTAGES: Can be used in a small, handheld device Faster results Higher precision ABSTRACT: Berkeley Lab researchers Andrew Wyrobek and Antoine Snijders have identified a panel of gene and protein biomarkers that will help … [Read more...] about Human Blood Molecular Biodosimeter Panel for Distinguishing Radiation Exposure from Inflammation Stress IB-3304
Genetically Encoded Sensors for Imaging Proteins and Their Complexes IB-3259
APPLICATIONS OF TECHNOLOGY: Fluorescent protein labeling for Medical diagnostics Drug screening Biology research ADVANTAGES: Smaller size than green fluorescent protein (GFP) Long fluorescence lifetime Extends convenient tagging and fluorescence anisotropy (FA) study for larger sized proteins Can be used for FA-imaging of target proteins in living … [Read more...] about Genetically Encoded Sensors for Imaging Proteins and Their Complexes IB-3259