APPLICATIONS OF TECHNOLOGY: Pharmaceutical / antibiotic discovery Phage therapy ADVANTAGES: Compared to current technologies Less expensive Less laborious Scalable Quantitative ABSTRACT: Researchers at the Berkeley Lab have developed two genetic technologies that enable fast and effective genome-wide screens for gene function. The LBNL … [Read more...] about High-Throughput Methods to Characterize Phage Receptors and Rational Formulation of Phage Cocktails 2019-048
Therapeutics
Production of Impurity-free Actinium-225 for Cancer Treatment 2019-040
APPLICATIONS OF TECHNOLOGY: Radiopharmaceuticals ADVANTAGES: Efficient, inexpensive, and scalable process No co-production of radioactive impurities to hinder use in patients Long half-life 4 α-decays capable of producing the sort of double-strand DNA damage needed to deter tumor growth Produces no long-lived radioactive products in its … [Read more...] about Production of Impurity-free Actinium-225 for Cancer Treatment 2019-040
Improving High Value Carotenoid Astaxanthin Production 2017-033
APPLICATIONS OF TECHNOLOGY: Human health and nutrition Biofuel feedstocks Food production ADVANTAGES: More economically viable means to produce microalgae Identifies specific genes required for astaxanthin antioxidant synthesis ABSTRACT: Researchers led by Melissa Roth of Howard Hughes Medical Institute and Krishna Niyogi of the Berkeley Lab have … [Read more...] about Improving High Value Carotenoid Astaxanthin Production 2017-033
Self-Assembling Protein Nanocage decorated with Antibodies (SAPNA) 2018-075
APPLICATIONS OF TECHNOLOGY: Biopharmaceuticals Cancer immunotherapy ADVANTAGES: Capable of interchanging antibodies, therefore, multi-functional Modular, available for use by human IgG1 and rabbit IgG antibodies Potential uses increase as more monoclonal antibody products developed ABSTRACT: Researchers at the Berkeley Lab have developed a … [Read more...] about Self-Assembling Protein Nanocage decorated with Antibodies (SAPNA) 2018-075
In vitro Assembly, Adhering Cargo to Bacterial Microcompartment (BMC) Shells 2017-131, 2016-150
APPLICATIONS OF TECHNOLOGY: Enables health care, industrial and other commercial uses of protein-based bacterial organelles (bacterial microcompartments (BMCs)) ADVANTAGES: Modular system for 2- and 3-dimensional scaffolds/compartments Defined composition, atomic-resolution structure known Robust, programmable encapsulation or polyvalent display of multiple … [Read more...] about In vitro Assembly, Adhering Cargo to Bacterial Microcompartment (BMC) Shells 2017-131, 2016-150