APPLICATIONS OF TECHNOLOGY: Enables health care, industrial and other commercial uses of protein-based bacterial organelles (bacterial microcompartments (BMCs)) ADVANTAGES: Modular system for 2- and 3-dimensional scaffolds/compartments Defined composition, atomic-resolution structure known Robust, programmable encapsulation or polyvalent display of multiple … [Read more...] about In vitro Assembly, Adhering Cargo to Bacterial Microcompartment (BMC) Shells 2017-131, 2016-150
Therapeutics
Specific Reduction of Various Isoprenoid Precursors and Isoprenoids by Geranylgeranyl Reductases 2018-088
APPLICATIONS OF TECHNOLOGY: Bio-derived platform chemicals for use in Pharmaceuticals Cosmetics and fragrances Fuels ADVANTAGES: Lower cost, bio-based pathway to high value chemicals Reduction of intermediates within the terpene biosynthesis pathway Production of higher quantity of farnesyl acetate ABSTRACT: Researchers at Berkeley Lab’s Joint … [Read more...] about Specific Reduction of Various Isoprenoid Precursors and Isoprenoids by Geranylgeranyl Reductases 2018-088
Producing Hydroxytyrosol in Engineered Escherichia Coli 2016-118
APPLICATIONS OF TECHNOLOGY: Dietary supplements Animal feed Antioxidant containing functional food ADVANTAGES: Stable and sustainable formation of antioxidants with high purity Provides a renewable microbial platform for production of a wide range of chemicals ABSTRACT: Joint BioEnergy Institute researchers led by Taek Soon Lee have developed a … [Read more...] about Producing Hydroxytyrosol in Engineered Escherichia Coli 2016-118
Selective Complexation and Separation of Tetravalent Metal Ions from Other Ions 2017-107
APPLICATIONS OF TECHNOLOGY: Nuclear energy or nuclear fuel reprocessing plants Pharmaceutical isotope production Pharmaceutical companies using lanthanide or actinide drugs Chemical industry ADVANTAGES: Highly selective Improved performance and reliability Versatile process Fewer steps ABSTRACT: Berkeley Lab researchers Rebecca Abergel and … [Read more...] about Selective Complexation and Separation of Tetravalent Metal Ions from Other Ions 2017-107
Thermostable RNA-Guided Endonucleases (GEOCAS9) 2017-117
APPLICATIONS OF TECHNOLOGY: Genome editing Genetic engineering Gene therapy Research tools (e.g., high-throughput screening of gene functions in cell lines and in vivo) Creation of transgenic animal models ADVANTAGES: Functions under different conditions than current CRISPR-Cas9 proteins (e.g, thermostable and enzymatically active in a wide temperature … [Read more...] about Thermostable RNA-Guided Endonucleases (GEOCAS9) 2017-117