APPLICATIONS OF TECHNOLOGY: Medical: Pharmaceuticals ADVANTAGES: Present strain is among the most robust constituents of the gut microbiome Obviates the need for exogenous iron-sulfur cluster producing genetic elements ABSTRACT: In 2018, Gizzi et al. demonstrated that the human gene Viperin can produce antiviral small molecules (ddhCTP) that act as a chain … [Read more...] about Gut Microbiome Engineering for the Heterologous Production of Antiviral Compounds 2019-085
Therapeutics
Polysaccharide Gel 2017-041
APPLICATIONS OF TECHNOLOGY: Food products Cosmetics Water and wastewater treatment Pharmaceuticals BENEFITS: Significantly lowers the costs of product recovery from cyanobacterial production strains Self-aggregating properties of the material streamline the processes of flocculation and clarification Enables novel encapsulation and drug formulation … [Read more...] about Polysaccharide Gel 2017-041
Peptoid-Based Chelating Molecules 2017-181
APPLICATIONS OF TECHNOLOGY: Radiolabeling Metal separation Water treatment ADVANTAGES: Robust chelators High selectivity ABSTRACT: Researchers at Berkeley Lab have developed a new class of chelators – molecules that can bind metals – that incorporate peptoids into the chelator backbone, offering more control over the chelator’s structure and ligands. … [Read more...] about Peptoid-Based Chelating Molecules 2017-181
High-Throughput Methods to Characterize Phage Receptors and Rational Formulation of Phage Cocktails 2019-048
APPLICATIONS OF TECHNOLOGY: Pharmaceutical / antibiotic discovery Phage therapy ADVANTAGES: Compared to current technologies Less expensive Less laborious Scalable Quantitative ABSTRACT: Researchers at the Berkeley Lab have developed two genetic technologies that enable fast and effective genome-wide screens for gene function. The LBNL … [Read more...] about High-Throughput Methods to Characterize Phage Receptors and Rational Formulation of Phage Cocktails 2019-048
Production of Impurity-free Actinium-225 for Cancer Treatment 2019-040
APPLICATIONS OF TECHNOLOGY: Radiopharmaceuticals ADVANTAGES: Efficient, inexpensive, and scalable process No co-production of radioactive impurities to hinder use in patients Long half-life 4 α-decays capable of producing the sort of double-strand DNA damage needed to deter tumor growth Produces no long-lived radioactive products in its … [Read more...] about Production of Impurity-free Actinium-225 for Cancer Treatment 2019-040