APPLICATIONS OF TECHNOLOGY: Treatment and prevention of gadolinium deposition in patients undergoing MRIs Treatment for exposure to toxic metals including lead, tin, and cadmium ADVANTAGES: Strong decorporation efficacy High affinity for the toxic elements gadolinium (Gd), lead (Pb), tin (Sn), and cadmium (Cd) ABSTRACT: Researchers at Berkeley Lab have … [Read more...] about Decorporation Agent for Therapeutic Chelation of Industrial and Clinical Toxic Heavy Metals 2016-078
Therapeutics
Oral Dosage Forms for Actinide Decorporation Agent 2016-079
APPLICATIONS OF TECHNOLOGY: Treatment of radionuclide exposure Treatment or prevention of gadolinium (Gd) deposition from MRIs Treatment for exposure to toxic metals including lead (Pb), tin (Sn), and cadmium (Cd) ADVANTAGES: Administered orally in a variety of dosage forms Ease of clinical use Enables use during emergencies or mass … [Read more...] about Oral Dosage Forms for Actinide Decorporation Agent 2016-079
A Novel 12-Gene Prognostic Signature for Breast Cancer 2016-181
APPLICATIONS OF TECHNOLOGY: Targeted cancer therapies Prediction of relapse-free survival ADVANTAGES: Determines most effective treatment options for patient quality of life Standardizes breast cancer prognoses ABSTRACT: A Berkeley Lab research team led by Antoine Snijders has identified a 12-gene signature that can be used to predict relapse-free … [Read more...] about A Novel 12-Gene Prognostic Signature for Breast Cancer 2016-181
Dub-seq: Double Barcoded Shotgun Expression Library Sequencing 2015-160
APPLICATIONS OF TECHNOLOGY: Drug discovery and screening Functional genomics Synthetic biology Enzyme discovery ADVANTAGES: High throughput Scalable Less labor intensive and expensive than current approaches Enables gene function annotation ABSTRACT: Though current functional genomics technologies coupled with next generation sequencing have … [Read more...] about Dub-seq: Double Barcoded Shotgun Expression Library Sequencing 2015-160
A Universal Approach to Integrate and Express Pathways in a Broad Range of Bacteria 2016-024
APPLICATIONS OF TECHNOLOGY: Microbiome engineering for medicine, agriculture, biomanufacturing and renewable energy Pharmaceutical synthesis Commodity chemical and biofuel production Livestock research and development ADVANTAGES: Enables high-throughput, stable, accurate, efficient gene integration and expression of very large DNA constructs (e.g., … [Read more...] about A Universal Approach to Integrate and Express Pathways in a Broad Range of Bacteria 2016-024